Professor Steve Jones paints a gloomy picture of human evolution at the end of the line with only gradual homogenisation towards universal brownness to look forward to. But in fact we are likely to be soon entering the most dynamic period of evolution – one in which humans will be able to transform their own biology by genetic engineering and gene therapy. Whereas all previous evolutionary innovation has relied on the slow and wasteful process of natural selection, mankind will soon be able to engineer his own biological destiny. This will eventually lead to an end to cancer, heart disease and even perhaps that most intractable of genetic diseases: death itself.
It is easy to imagine situations where genetic modification to produce so-called designer babies could be considered to be a good thing. In the UK, about one in 33 babies are born with a genetic disease. Some of these will be relatively mild conditions but many, like cystic fibrosis or muscular dystrophy, will be terminal or severely debilitating. It is now possible, using pre-implantation genetic diagnosis (PGD), to examine an embryo generated by IVF and detect the presence of the defective gene. This is currently performed in a number [...] Continue Reading…
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October 13th, 2008
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Pending Mr Right’s arrival, I had my eggs frozen. But will putting a baby on hold be worth it?
Fleur Britten
At age 34, I’m having a panic attack. I might be biologically ready for procreation — past ready, even — but, emotionally, I’m committed to my career, not to The One. I’m still asking, which One? I exist in that “30 is the new 20” generation: perfection-seeking, commitment-phobic and no way near ready. But I need to insure against finding myself in a Tracey Emin moment, choked by my childlessness at 40. Twenty-three per cent of women born in 1973 won’t have had children by the time they hit 45. By which time it might be too late. I need to put my fertility on ice, before it runs out on me. So I’m having my eggs frozen. Read more,
Source: TimeOnline, UK
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October 12th, 2008
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Department of Urology and Reproductive Medicine, Weill Medical College of Cornell University, New York, NY 10065, USA.
Klinefelter syndrome, 47,XXY and its variants, is the most common chromosomal aberration among men, with estimated frequency of 1: 500 among newborns. Men with Klinefelter syndrome present with sequels of hormonal and spermatogenic testicular failure like infertility, low testosterone, erectile dysfunction, and low bone mineral density. This review is aimed to provide the practicing urologist with an important source of clinically relevant information about Klinefelter syndrome.
Sperm can be found in over 50% of men with Klinefelter syndrome, thus men with Klinefelter syndrome are not sterile. Recent evidence suggests that children with Klinefelter syndrome are born with spermatogonia and lose large numbers of germ cells during puberty. Early diagnosis and treatment can improve the quality of life and the overall health of men with Klinefelter syndrome.
Growing interest in Klinefelter syndrome among translational scientists and clinicians will result in better understanding of the pathophysiology of testicular failure. In some states, screening programs for Klinefelter syndrome are already in place, which will increase the number of patients with Klinefelter syndrome seen by practicing urologists in the near future. Diagnosis and management of patients with Klinefelter [...] Continue Reading…
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October 9th, 2008
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Despite a recent report on Chicago’s toxic air and another report on pollution’s threat on sperm mobility, evidence doesn’t suggest the fertility of Chicago men is affected.
Ahmad Hammoud, a researcher at the University of Utah’s Division of Reproductive Endocrinology and Infertility, released preliminary findings last week showing that a chemical in air pollution may disrupt sperm’s ability to move.
Hammoud’s research was released just days before the Chicago Tribune’s report on Chicago’s noxious air—some of the most threatening in the nation.
However, Edward Marut, medical director of Fertility Center of Illinois/Highland Park IVF Center, and Hammoud agree that Chicago men with normal sperm quality shouldn’t be concerned.
“We’re not all of a sudden going to have a group of otherwise fertile guys suddenly not able to father children,” Marut said. “It’s not so devastating in general, but there is going to probably be a population with borderline sperm quality who is definitely going to be affected by it.” more…
Source: The Medill Reports
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October 5th, 2008
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