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You are here: Home  Fertility News News Heavy smoking reduces success of IVF treatment |
| Heavy smoking reduces success of IVF treatment |
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| Wednesday, 04 April 2007 | |
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Heavy smoking may actually prevent the successful implantation of an embryo in the wall of the womb after IVF treatment, according to a new study published online by the journal Human Reproduction. Fertility experts said that the heavy smoking is not conducive to getting pregnant through IVF.
Researchers from Portugal and Spain found that 52.2 percent non-smokers or light smokers were able to get pregnant at the first time of the treatment compared to only 34 percent of the women who smoked 10 or more cigarettes a day. "The fact that we see this result in a situation in which the oocytes (eggs) were donated by other women demonstrates that cigarette smoking negatively affects the receptiveness of the uterus independently of its effect on ovarian function," said lead researcher Dr Sérgio Soares of the IVI Clinic in Lisbon. The researchers said that tobacco might prevent the uterus from being receptive to the embryo. The problem is that after IVF treatment even if the egg is fertilized, chances of a successful pregnancy are remote in heavy smokers, the researchers said. In the study the researchers compared the success rates of in-vitro fertilization (IVF) treatment in 44 heavy smokers and 785 women who did not smoke or smoked in negligible amounts. "The non-heavy smokers had a significantly higher pregnancy rate, with over half becoming pregnant (52.2 percent), compared with just over a third (34.1 percent) of the heavy smokers," Soares said. Surprisingly the heavy smokers have an increased rate of multiple births, the researchers said. Around 60 percent of the heavy smokers had multiple births as compared to just 31 percent of non-smokers or light smokers. Dr Soares said that larger studies are needed to analyze the effect of tobacco on the uterus. "It is already known that there is paradoxical dose-dependent effect of nicotine on ovarian tissue. Maybe the same effect is happening in uterine tissues," he theorized. Copyright © 2007 Respective Author |
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